Suruchi Sharma
Diabetes is a condition that impacts various body systems, leading to weight gain and muscle effects.
The development of disorders like type 2 diabetes is linked to mitochondrial abnormalities.
Individuals with this condition either cannot produce sufficient insulin or cannot effectively use the insulin they produce to regulate normal blood sugar levels.
Scientists at the University of Michigan demonstrated using mice that inactive mitochondria initiate a reaction influencing the development and performance of B-cells.
Numerous research studies have indicated that the insulin-producing B-cells in diabetic patients have dysfunctional mitochondria and cannot produce energy.
Mitochondria generate energy, supplying fuel to cells and ensuring their proper function.
The team repeated their experiments on liver cells and fat storage cells, observing the activation of the same stress response. Neither type of cell was able to mature or function correctly.
The researchers discovered that mitochondrial damage does not cause cell death, regardless of the cell type.